Mischievous websites and spyware programs often open program windows that do not include the usual X button to close them. Rather than being tricked into clicking in the program window, Windows users can use Alt-F4 to close the current window. The Alt-F4 trick can also be used to close errant programs that are not responding to other mouse clicks.
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Feldman, Barbara. "Alt-F4." Surfnetkids. Feldman Publishing. 14 Sep. 2004. Web. 21 Nov. 2014. <http://www.surfnetkids.com/tech/124/alt-f4/ >.